THIRONA

AI-powered CT analysis for respiratory clinical trials

Thirona provides advanced AI-powered quantitative analysis of chest CT scans, supporting pharmaceutical companies in accelerating respiratory drug development across clinical trial phases.

Quantitative CT analyses and treatment efficacy assessment

With advanced, extensively validated anatomical segmentation and quantification methods, Thirona’s LungQ® analyses deliver precise measurements of anatomical lung structures, including parenchyma, airways and vasculature.

Enabling detailed local assessment of lung conditions such as emphysema, air trapping, bronchial dilatation, mucus plugging, and other clinically relevant features, the objective data generated by Artificial Intelligence, can help significantly improve trial efficiency and strengthen regulatory approval process.

  • In Phase I and II trials, AI-powered image analysis can help detect early treatment signals and refine patient selection.
  • In Phase III and IV, it may offer more precise efficacy assessments and support long-term disease monitoring.

Thirona’s therapeutic areas of expertise cover all major lung diseases, including:

  • COPD
  • Severe Asthma
  • Cystic Fibrosis
  • Bronchiectasis disease
  • ILD

Examples of LungQ® AI analyses

Emphysema severity

Chronic perfusion defect

Bronchial wall thickening

Mucus plugs

Robust clinical research evidence

With more than 200 scientific publications and 24,000 patients analyzed in cohort studies and randomized controlled trials across diseases, Thirona’s AI analyses are backed by extensive clinical evidence, demonstrating consistently high performance in real-world settings.

See the list of publications.

Featured talk

Advancing Bronchiectasis Clinical Trials with AI-powered Image Analysis

Prof. Harm Tiddens, MD, PhD — Chief Medical Officer, Thirona

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We are pleased to share that the abstracts from the 8th World Bronchiectasis Conference will be published on the scientific journal Pulmonary Medicine.

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